The smart Trick of ceesdekker That Nobody is Discussing
The smart Trick of ceesdekker That Nobody is Discussing
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Making use of single-molecule optical and AFM imaging and drive-spectroscopy procedures, we search for to unravel the mechanistic facets of the construction and dynamics of chromosomes. Our research pursuits include things like:
1996, 1st mesoscopic demand density waves gadgets; and initially electrical measurements on a single metal nanocluster involving nanoelectrodes
[Laughs] ‘It was undoubtedly a fantastic threat! At time, I was well aware that it could go wrong Which I could develop into a lot less productive, but I just dismissed that. Curiosity has usually been my strongest driving force. And luckily everything labored out.’
Our perform was speedily adopted up by Many others, most notably by Phaedon Avouris and colleagues at IBM, who in Oct 1998 posted their conclusions on transistors made from single- and multi-walled carbon nanotubes in Applied Physics Letters.
2012, discovery that nucleoid occlusion underlies the accuracy of bacterial mobile division; and initial at any time research with the dynamics DNA supercoils and the invention of supercoil hopping
The coiled-coil of your human Rad50 DNA mend protein consists of specific segments of greater versatility
Due to the fact 2000 he moved to solitary-molecule biophysics and nanobiology, with analysis from DNA supercoiling research of nucleosomes and DNA repair proteins to DNA translocation as a result of nanopores. Not long ago his investigation has focused on researching mobile division with germs on chip, though his best fascination is within the way of noticing synthetic cells.
2000, discovery that nanotubes can have incredible huge latest densities; settled the controversial challenge of electronic transport by DNA molecules by measurements of insulating behavior at the single molecule stage; and demonstration of the AFM method for solitary-molecule manipulation of nanotubes
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At the moment, we also realized that it should be possible to make use of just one semiconducting carbon nanotube to produce a transistor — and we set out to make it. We stretched unique semiconducting nanotubes throughout metallic electrodes and applied the underlying silicon substrate like a gate electrode, setting up the basic a few-terminal format of a area-effect transistor (Fig.
Case in point (four) of bending configurations in 3D simulations of DNA rods on nanopores. A part of the membrane is proven in gray, the rim of your pore is highlighted in purple, along with a 3D rendering of the movement on the DNA rod is shown.
Later on we spoke again briefly due https://www.ceesdekker.net to the fact Dekker felt that our dialogue of his religion quickly became purely philosophical, While What's more, it concretely helps him in his function.
Visualization of unstained DNA nanostructures with State-of-the-art in-aim transmission electron microscopy methods
Ultimately, I will briefly sketch several of our Strategies to explore the developing of synthetic cells, especially our 1st methods to determine artificial mobile division.